Research progress on bipolar disorder and pregnancy complications and neonatal risk
10.3969/j.issn.1002-0152.2024.01.011
- VernacularTitle:双相障碍与妊娠期并发症及新生儿患病风险研究进展
- Author:
Yulin ZHANG
1
;
Xiaoling FENG
Author Information
1. 黑龙江中医药大学研究生院(哈尔滨 150040)
- Keywords:
Bipolar disorder;
Major depression;
Mania;
Pregnancy complications;
Neonatal morbidity
- From:
Chinese Journal of Nervous and Mental Diseases
2024;50(1):60-64
- CountryChina
- Language:Chinese
-
Abstract:
Pregnant women with bipolar disorder(BD)are a high-risk pregnancy state.Necessary psychotropic drug treatment,special stress reactions,bad living habits,and fluctuations in pregnancy hormones all increase the risk of pregnancy to a certain extent.Risks of complications such as hypertension,gestational diabetes,premature birth and spontaneous abortion.Drugs can penetrate the placental blood-brain barrier and enter the maternal-fetal microcirculation.Combined with the effects of genetic genes and the environment,they can induce neurodevelopmental abnormalities in the fetus,leading to congenital malformations,attention deficit hyperactivity disorder,autism spectrum disorder and other diseases after birth.The mode of delivery may also be affected.Women with BD often give birth by caesarean section.It is particularly important to weigh the choice of drug types and dosages,which will help improve the accuracy of clinical risk management and disease control of pregnancy-related mental disorders.
