Research progress of transcranial alternating current stimulation in the treatment of cognitive impairment in neuropsychiatric diseases
10.3969/j.issn.1002-0152.2024.01.008
- VernacularTitle:经颅交流电刺激治疗神经精神疾病认知功能损害研究进展
- Author:
Xuelin ZHANG
1
;
Qiuli YANG
;
Xiaying SI
;
Peishan HUANG
;
Ke WANG
;
Yi MIAO
;
Qiangli DONG
Author Information
1. 兰州大学第二医院心理卫生科(兰州 730000)
- Keywords:
Transcranial alternating current stimulation;
Neural oscillation;
Mechanism of action;
Cognitive func-tion;
Alzheimer disease;
Neuropsychiatric disease;
Research progress
- From:
Chinese Journal of Nervous and Mental Diseases
2024;50(1):43-48
- CountryChina
- Language:Chinese
-
Abstract:
Cognitive dysfunction is the impairment of higher brain functions.Cognitive impairment caused by neuropsychiatric diseases has caused serious impact on patients'quality of life and the outcome of the disease.The transcranial alternating current stimulation(tACS)improves cognitive function by modulating neural oscillations of specific frequencies,affecting the release of neurotransmitters such as serotonin and dopamine,and enhancing local and distal synchronization of brain networks.Specific frequencies of tACS can improve the cognitive impairment caused by Alzheimer disease(AD),schizophrenia,and depression,among which the gamma and theta frequencies of tACS have the most significant effects on cognitive function.tACS has high safety and low operational difficulty,and has great potential to improve cognitive function.