Research progress in the treatment of speech disorders in patients with Parkinson disease by repetitive tran-scranial magnetic stimulation

VernacularTitle:重复经颅磁刺激治疗帕金森病言语障碍研究进展
Author: Mingqi WANG ¹ ; Zhenchun SHI ; Lei SU
Author Information

1. 山东省精神卫生中心康复治疗科(济南 250014)
Keywords: Parkinson disease; Speech disorders; Transcranial magnetic stimulation; Motor cortex; Temporal lobe; Prefrontal cortex
From: Chinese Journal of Nervous and Mental Diseases 2024;50(1):38-42
CountryChina
Language:Chinese
Abstract: Up to 90%of patients with Parkinson disease(PD)experience speech disorders that seriously affect quality of life.The new progress has been made on repetitive transcranial magnetic stimulation(rTMS)in the clinical practice of treating speech disorders in patients with PD in recent years.The studies showed that applying rTMS to the orofacial region of the primary motor cortex(M1)and the superior temporal gyrus(STG)could safely and effectively improve speech function of patients with PD with no reported side effects.The underlying mechanism may relate to ability of rTMS to modulate the degree of excitability and functional connectivity in speech-associated cerebral cortices,such as M1 and STG.In conclusion,rTMS has exhibited encouraging outcomes in managing speech disorders in patients with PD.However,the number of studies is still insufficient and more large-scale randomized controlled trials with large sample sizes are needed in the future to further support the findings of this review.