Clinical distribution of primary intracranial tumors and risk factors for postoperative complications
10.3969/j.issn.1002-0152.2023.11.003
- VernacularTitle:原发性颅内肿瘤临床分布及术后并发症危险因素
- Author:
Shasha LI
1
;
Huawei HUANG
;
Yuan YUAN
;
Yucui XI
;
Ran ZHANG
;
Yuhua HOU
Author Information
1. 首都医科大学附属北京天坛医院重症医学科,国家神经病学研究中心,北京市神经外科研究所(北京 100070)
- Keywords:
Primary intracranial tumor;
Clinical distribution;
Glioma;
Meningioma;
Neurilemmoma;
Postopera-tive complications;
Coagulation function;
Intracranial infection;
Risk factor
- From:
Chinese Journal of Nervous and Mental Diseases
2023;49(11):654-658
- CountryChina
- Language:Chinese
-
Abstract:
Objective To examine the clinical distribution of primary intracranial tumors and analyze the risk factors for postoperative complications.Methods From January 2018 to December 2022,the clinical data of 961 patients with primary intracranial tumor in the Department of Neurosurgery of Tiantan Hospital in Beijing were collected and analyzed retrospectively.To examine the clinical distribution of patients with primary intracranial tumor and present the incidence of postoperative complications.To compare the basic data of patients with and without postoperative complications,and analyze the risk factors leading to postoperative complications.Results There were 363 cases of glioma,231 cases of meningioma,158 cases of sellar tumors,142 cases of neurilemmoma and 67 cases of other types of tumors.There were 679 cases of supratentorial tumors and 282 cases of infratentorial tumors.Postoperative complications occurred in 279 patients,and the incidence of postoperative complications was 29.03％.The incidences of intracranial infection,pulmonary infection,hyponatremia,lower extremity venous thrombosis and central nervous system infection were 9.37％,5.41％,4.99％,4.47％and 4.27％,respectively.After surgery,D-dimer(D-D),fibrin degradation products(FPD),prothrombin time(PT)in patients with primary intracranial tumors were significantly higher than those in patients without primary intracranial tumors(P<0.05).Activation of partial thromboplastin time(APTT),and thrombin time(TT)levels were significantly higher than those before surgery(P<0.05).Fibrinogen(FIB)was significantly lower than that before surgery(P<0.05).There were significant differences in tumor location,intraoperative blood loss,operation time,anesthesia recovery time and postoperative coagulation function between patients with and without postoperative complications(P<0.05).Conclusions The common types of primary intracranial tumors include gliomas,meningiomas,sellar tumors and neurilemmoma,etc.Surgical treatment has a high risk of postoperative complications.Common postoperative complications include intracranial infection,pulmonary infection,hyponatremia,lower extremity venous thrombosis,and central nervous system infection.Tumor location,operation duration,intraoperative blood loss,anesthesia recovery time and postoperative coagulation dysfunction are all risk factors for postoperative complications.
