A case report of multiple myeloma complicated with primary systemic light amyloidosis peripheral neuropa-thy
10.3969/j.issn.1002-0152.2023.09.005
- VernacularTitle:多发性骨髓瘤合并原发性系统性轻链淀粉样变性周围神经病变1例
- Author:
Chunjia WU
1
;
Hanzhe ZHANG
;
Donghui SHEN
;
Haifeng WANG
;
Weijie ZHANG
;
Xin WANG
Author Information
1. 潍坊医学院临床医学院(潍坊 261053)
- Keywords:
Primary systemic light chain amyloidosis(AL);
Systemic amyloidosis;
Peripheral neuropathy;
Mul-tiple myeloma;
Electromyography
- From:
Chinese Journal of Nervous and Mental Diseases
2023;49(9):539-543
- CountryChina
- Language:Chinese
-
Abstract:
This paper reports a case of multiple myeloma complicated with Primary systemic light chain amyloidosis peripheral neuropathy.Patient was a male,60 years old with subacute onset of peripheral neuropathy.Patient had previous history of hypertension,coronary heart disease and stable angina pectoris.His urine routine examination 2 months ago showed urine protein(+++).The first clinical symptom with peripheral neuropathy characterized by progressive numbness and weakness of both lower limbs.The diagnosis was made after completing electromyography,lumbar puncture,renal puncture,bone puncture and other related examinations,and relevant treatment was given.As a rare disease of nervous system,the incidence rate is low.Early diagnosis is an important step to reduce mortality and improve prognosis.However,the disease is easily misdiagnosed as diabetic peripheral neuropathy and chronic inflammatory demyelinating polyradiculoneuropathy,thereby delaying diagnosis and treatment.
