Application of single nucleotide polymorphism(SNP)analysis in bacterial molecular typing
10.3969/j.issn.1002-2694.2023.00.139
- VernacularTitle:单核苷酸多态性(SNP)分析在细菌分子分型中的应用
- Author:
Fu-Ping YANG
1
,
2
;
Xiang-Dong YANG
;
Bin-Bin YU
;
Zi-Hou GAO
Author Information
1. 大理大学,大理 671000
2. 云南省地方病防治所,云南省自然疫源性疾病防控技术重点实验室,大理 671000
- Keywords:
SNP;
bacteria;
molecular typing
- From:
Chinese Journal of Zoonoses
2023;39(12):1196-1201,1210
- CountryChina
- Language:Chinese
-
Abstract:
Single nucleotide polymorphisms(SNPs),third generation molecular genetic markers,have attracted extensive attention because of their importance in research on genetic diseases,gene evolution,adaptation,species,medicine and other fields.SNPs are found in large numbers,with a wide distribution,stable genetics and high throughput.Moreover,SNPs are suitable for rapid and large-scale screening.These genetic markers have been widely used in molecular typing for a variety of bacteria.Herein,the current status of SNP technology is discussed and compared with other typing methods,and its applica-tions in bacterial molecular typing are reviewed.