Research progress on extracellular vesicles of Gram-positive bacteria
10.3969/j.issn.1000-484X.2023.12.032
- VernacularTitle:革兰氏阳性菌细胞外囊泡研究进展
- Author:
Zhaokun XU
1
,
2
;
Min LI
;
Haixia LUO
Author Information
1. 宁夏大学西部特色生物资源保护与利用教育部重点实验室,银川 750021
2. 宁夏大学生命科学学院,银川 750021
- Keywords:
Gram-positive bacteria;
Extracellular vesicles;
Functions;
Applications
- From:
Chinese Journal of Immunology
2023;39(12):2646-2655
- CountryChina
- Language:Chinese
-
Abstract:
Extracellular vesicles(EVs)are membrane-derived lipid bilayers secreted by bacteria and eukaryotic cells.EVs se-creted by Gram-negative bacteria have been extensively studied for many years,but due to differences in cell wall structure,EVs in Gram-positive bacteria have been disregarded.However,the production of EVs in Gram-positive bacteria was confirmed in recent stud-ies.Components of EVs are diverse,including proteins,lipids,nucleic acids and metabolites,play important role in biofilm forma-tion,antibiotic resistance,horizontal gene transfer(HGT)and pathogenesis.EVs have potential applications and are involved in the fields of vaccine research and development,disease treatment and drug delivery.Here,we review the latest findings on the biogene-sis,components,applications and functions of EVs from Gram-positive bacteria,hoping to provide a reference for the research in the field of EVs in Gram-positive bacteria.
