Research progress of intestinal innate immunity and diabetes mellitus
10.3969/j.issn.1000-484X.2023.12.031
- VernacularTitle:小肠固有免疫与糖尿病的研究进展
- Author:
Linyue ZHOU
1
;
Xuehui LIU
;
Yan LIU
;
Huanan JIA
;
Xuhong MA
;
Chunguang XIE
Author Information
1. 成都医学院公共教学中心,成都 610500
- Keywords:
Diabetes mellitus;
Intestinal;
Innate immune
- From:
Chinese Journal of Immunology
2023;39(12):2638-2645
- CountryChina
- Language:Chinese
-
Abstract:
Diabetes mellitus(DM),as a common and frequently-occurring disease,has become a huge burden of chronic diseases worldwide,whose pathogenesis is very complex and has not yet been fully elucidated.Small intestine is one of important immune organ in body,and relationship between its innate immune function and DM has become forefront of research in medical field.In this paper,role of intestinal innate immunity in pathogenesis of DM is reviewed,including tissue barrier dysfunction of small intestine,dysfunction of intestinal innate immune cells and imbalance of proportion of intestinal innate immune molecules,in order to provide references for future research on related mechanisms.
