Effects of obesity on vascular anatomy and post-operative outcomes in patients undergoing carotid artery stenting
10.3760/cma.j.cn115822-20230428-00070
- VernacularTitle:肥胖对接受颈动脉支架置入手术患者血管解剖形态和术后结局的影响
- Author:
Tianhua FAN
1
;
Liansheng MA
Author Information
1. 山西医科大学第一临床医学院研究生处，太原 030001
- Keywords:
Obesity;
Carotid artery stenting;
Vascular anatomy;
Intermediate variables
- From:
Chinese Journal of Clinical Nutrition
2023;31(5):294-299
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of obesity on vascular anatomy and post-operative outcomes in patients undergoing carotid artery stenting (CAS), and to inform the choice of treatment options for obese patients.Methods:Patients who underwent CAS in the Stroke Center of First Hospital of Shanxi Medical University between January 1st, 2020 and December 31st, 2022 were collected, and their medical records and digital subtraction angiography images were collected. All patients were divided into obese group and non-obese group based on the body mass index at admission. Vascular anatomy and the incidence of peri-operative adverse outcomes were compared between the two groups. The three-step regression method was used to further explore the role of vascular anatomy in the correlation between obesity and peri-operative adverse outcomes in CAS.Results:A total of 298 patients were included. The Buffalo Risk Assessment Scale index was higher for the obese group, and high-risk vascular anatomy was more common in the obese group( P<0.05). The incidence of peri-operative stroke in the obese group was higher than that in the non-obese group (18.5% vs. 5.2%, P=0.007). The mediation analysis suggested the full mediation effect of high-risk vascular anatomy on obesity to influence the incidence of peri-operative stroke after CAS. Conclusion:Obesity increases the risk of post-operative adverse outcomes via inducing the development of complex vascular anatomy.
