Optimization of energy window of yttrium-90 bremsstrahlung SPECT imaging:In vitro experimental study
10.13929/j.issn.1672-8475.2024.03.010
- VernacularTitle:优化钇-90轫致辐射SPECT显像能窗:体外实验研究
- Author:
Wendi CHENG
1
;
Yongzhao XIANG
;
Haitao WANG
;
Weiming WU
;
Jingjing YANG
;
Huawei CAI
;
Zhen ZHAO
Author Information
1. 四川大学华西医院核医学科,四川 成都 610041
- Keywords:
yttrium radioisotopes;
tomography,emission-computed,single-photon
- From:
Chinese Journal of Interventional Imaging and Therapy
2024;21(3):175-178
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the influence of different energy windows of the medium-energy general-purpose(MEGP)collimator on image quality,so as to optimize the energy window of yttrium-90(90Y)bremsstrahlung SPECT imaging.Methods 90Y bremsstrahlung spectrum was acquired,and the sensitivity,percentage of the source counts in useful field of view(S/FOV%)and signal-to-background ratio(S/B)of 90Y bremsstrahlung SPECT imaging at MEGP under different energy windows were compared.Results The energy spectrum of 90Y bremsstrahlung was a continuous curve,with the peak of 76.2 keV with MEGP collimator.The images obtained with MEGP collimator were clear,and no significant differences of S/FOV%nor S/B was found between 10%and 20%window width groups(both P＞0.05),but the sensitivities of the latter was higher than the former(P＜0.05).The sensitivity of 70-90 keV images was relatively high,while the S/FOV%and S/B had decreased.The S/FOV%and S/B of images ranging from 40-60 keV were high,but the sensitivity was low.Images acquired with 100 keV±20%showed fairly high sensitivity,S/FOV%and S/B,which was 69.73%,0.62 and 1.64,respectively.Conclusion When performing 90Y bremsstrahlung SPECT with MEGP collimator,the image quality at 20%window width was better than at 10%window width,and 100 keV±20%showed fairly high sensitivity and not significantly decreased S/FOV%and S/B.
