Correlation of neutrophil/lymphocyte ratio with cardiac function and prognosis in patients with acute myocardial infarction after percutaneous coronary intervention
10.3760/cma.j.cn341190-20230615-00528
- VernacularTitle:NLR与AMI患者PCI后心功能和预后的相关性研究
- Author:
Xiaoming YANG
1
;
Xiang ZHENG
;
Dakai CHEN
Author Information
1. 温州市中西医结合医院心血管内科，温州 325000
- Keywords:
Myocardial infarction;
Percutaneous coronary intervention;
Granulocytes;
Lymphocytes;
Heart function tests;
Myocardial reperfusion injury
- From:
Chinese Journal of Primary Medicine and Pharmacy
2024;31(2):165-169
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To correlate neutrophil/lymphocyte ratio (NLR) with cardiac function in patients with acute myocardial infarction (ACI) after percutaneous coronary intervention (PCI) and investigate its clinical value in predicting major adverse cardiovascular events (MACEs) in patients.Methods:A total of 120 patients with AMI who underwent PCI at Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine from March 2020 to February 2023 were included in this prospective study. The difference in NLR measured 1 day after PCI relative to that measured at 5 days after surgery (?NLR) was correlated with cardiac function ultrasound indicators measured at 3 months after surgery, myocardial injury, and inflammatory biochemical indicators at 1 day after surgery. The MACEs occurring within 3 months after surgery were recorded. The value of ΔNLR recorded during the early stage after PCI for predicting MACEs in patients with AMI was evaluated.Results:At 3 months after surgery, 13 out of 120 patients with AMI (10.83%) had MACEs. The ?NLR in patients with AMI who had MACEs was (3.55 ± 0.47), which was significantly higher than (2.06 ± 0.34) in patients with AMI who had no MACEs ( t = 17.25, P < 0.001). An optimal critical value of ?NLR for predicting MACEs after PCI in patients with AMI was 2.75, with an area under the receiver operating characteristic curve of 0.972, a sensitivity of 90.70%, and a specificity of 91.10%. Conclusion:Increased NLR during the early stage after PCI in patients with AMI is closely related to decreased cardiac function, and worsened myocardial injury and inflammatory reactions. Changes in NLR after PCI in patients with AMI have a highly valuable value for predicting MACEs in these patients.
