Susceptibility factors of occurrence of allergic rhinitis
10.3760/cma.j.cn341190-20221208-01009
- VernacularTitle:变应性鼻炎发病相关易感因素的调查研究
- Author:
Yuanhua LIU
1
;
Yueyuan XU
;
Jieqing YU
;
Jing YE
;
Huarong YI
Author Information
1. 南昌大学第一附属医院耳鼻咽喉头颈外科，南昌 330006
- Keywords:
Rhinitis,allergic,perennial;
Disease susceptibility;
Surveys and questionnaires;
Cross-sectional studies;
Family health;
Environmental health;
Disease
- From:
Chinese Journal of Primary Medicine and Pharmacy
2023;30(11):1624-1629
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the genetic and environmental factors that may contribute to the development of allergic rhinitis (AR) in patients, and provide a scientific basis for formulating intervention measures.Methods:This is a case-control study. A cross-sectional survey was conducted on AR patients who received treatment at The First Affiliated Hospital of Nanchang University from June 2017 to March 2019 using a self-designed questionnaire on AR susceptibility factors. Logistic regression analysis of AR susceptibility factors was performed.Results:There were 242 patients in the AR group and 258 patients in the non-AR group (control group). The average age of all patients was (13.16 ± 5.63) years. 56.8% of included patients were male. Multivariate logistic regression analysis showed that AR onset was associated with neonatal jaundice ( OR = 6.043), respiratory infections within 6 months after birth ( OR = 8.123), diarrhea ( OR = 3.868), eczema ( OR = 4.540), living in urban areas ( OR = 2.477), home decoration after birth ( OR = 3.042), moldy ceilings or walls ( OR = 38.255), home gardening ( OR = 3.752), and exposure to smoking environments ( OR = 2.574). Conclusion:The etiology of AR is complex, and its onset is influenced by various factors such as genetic factors, environmental factors, and related disease factors. It is necessary to strengthen the promotion and education of AR prevention knowledge, pay attention to environmental hygiene, and take personal protection measures.
