Healthcare-associated infection and pathogen spectrum in neonatal inten-sive care unit:a 5-year single-center study
10.12138/j.issn.1671-9638.20244603
- VernacularTitle:新生儿重症监护病房医院感染与病原菌谱:一项单中心五年研究
- Author:
Yan-Min LI
1
;
Rui-Min ZHANG
;
Li-Li PING
;
Li-Na ZHAI
;
Xiao-Li ZHANG
;
Jun-Yue HAN
Author Information
1. 河北北方学院研究生学院,河北张家口 075000
- Keywords:
neonate;
neonatal intensive care unit;
healthcare-associated infection;
pathogen
- From:
Chinese Journal of Infection Control
2024;23(2):195-200
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the spectrum and changes of pathogens causing healthcare-associated infec-tion(HAI)in neonatal intensive care unit(NICU).Methods Clinical medical records of neonates with HAI in a hospital from January 2018 to December 2022 were collected,spectrum of pathogens causing HAI were and analyzed retrospectively.Results A total of 7 597 hospitalized neonates were investigated,and 240 of whom had 263 cases of HAI,with an HAI incidence of 3.16％and healthcare-associated case infection incidence of 3.46％.96 cases(36.50％)were bloodstream infection,70(26.62％)were respiratory system infection,and 57(21.67％)were in-fection without clear sites.A total of 170 pathogens were detected from specimens,78(45.88％)of which were Gram-positive bacteria,with Staphylococcus spp.accounting for the highest proportion,78(45.88％)were Gram-negative bacteria,mainly Klebsiella pneumoniae,and 14(8.24％)were fungi.The detection rate of Gram-negative bacteria showed an upward trend from 2018 to 2022(P＜0.01).Conclusion The majority of HAI in NICU is bloodstream infection.In recent years,the detection rate of Gram-negative bacteria has been increasing year by year,and it is necessary to streng-then the prevention and control of HAI in clinical practice.
