A multicenter retrospective cohort study on the attributable risk of patients with Acinetobacter baumannii sterile body fluid infection
10.12138/j.issn.1671-9638.20243007
- VernacularTitle:鲍曼不动杆菌无菌体液感染患者归因危险度多中心回顾性队列研究
- Author:
Lei HE
1
;
Dao-Bin JIANG
;
Ding LIU
;
Xiao-Fang ZHENG
;
He-Yu QIU
;
Shu-Mei WU
;
Xiao-Ying WU
;
Jin-Lan CUI
;
Shou-Jia XIE
;
Qin XIA
;
Li HE
;
Xi-Zhao LIU
;
Chang-Hui SHU
;
Rong-Qin LI
;
Hong-Ying TAO
;
Ze-Fen CHEN
Author Information
1. 重庆市大足区人民医院感染控制科,重庆 402360
- Keywords:
Acinetobacter baumannii;
attributable risk;
prognosis;
sterile body fluid;
blood;
multicenter cohort study
- From:
Chinese Journal of Infection Control
2024;23(1):42-48
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the attributable risk(AR)of Acinetobacter baumannii(AB)infection in criti-cally ill patients.Methods A multicenter retrospective cohort study was conducted among adult patients in inten-sive care unit(ICU).Patients with AB isolated from sterile body fluid and confirmed with AB infection in each cen-ter were selected as the infected group.According to the matching criteria that patients should be from the same pe-riod,in the same ICU,as well as with similar APACHE Ⅱ score(±5 points)and primary diagnosis,patients who did not infect with AB were selected as the non-infected group in a 1:2 ratio.The AR was calculated.Results The in-hospital mortality of patients with AB infection in sterile body fluid was 33.3％,and that of non-infected group was 23.1％,with no statistically significant difference between the two groups(P=0.069).The AR was 10.2％(95％CI:-2.3％-22.8％).There is no statistically significant difference in mortality between non-infected pa-tients and infected patients from whose blood,cerebrospinal fluid and other specimen sources AB were isolated(P＞0.05).After infected with AB,critically ill patients with the major diagnosis of pulmonary infection had the high-est AR.There was no statistically significant difference in mortality between patients in the infected and non-infec-ted groups(P＞0.05),or between other diagnostic classifications.Conclusion The prognosis of AB infection in critically ill patients is highly overestimated,but active healthcare-associated infection control for AB in the ICU should still be carried out.
