Study on the population genetic structure and phylogenetic relationship of the Han population in Dalian
10.13618/j.issn.1001-5728.2024.01.015
- VernacularTitle:大连汉族群体遗传结构及系统关联性的研究
- Author:
Wenqian SONG
1
;
Shihang ZHOU
;
Nan XIAO
;
Lingzi PAN
;
Linnan SHAO
;
Yuexin XIA
;
Ying DUAN
;
Yicheng YANG
;
Chunxiang LI
;
Weijian YU
Author Information
1. 大连市血液中心,司法鉴定所,辽宁大连 116001
- Keywords:
Population genetics;
Y-STR;
Genetic distance
- From:
Chinese Journal of Forensic Medicine
2024;39(1):88-93
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the population genetic structure and phylogenetic relationships by combining Y-STR haplotype genetic information from the Han population in Dalian with 32 domestic and foreign groups.Methods Blood samples of 958 Han male volunteers from Dalian were collected.Genetic typing of 42 genetic loci was completed using Y-STR fluorescent reagent kits and capillary electrophoresis.Related forensic parameters were calculated.Nei's standard genetic distances among 33 populations based on 17 Y-STR loci were computed,in order to create a principal coordinate analysis as well as construct a phylogenetic tree.Results The analysis of genetic polymorphisms at 42 Y-STR loci revealed 30 unconventional alleles at 10 loci.Genetic analysis of the population based on 17 Y-STR loci confirmed that Dalian's Han population had the closest genetic distance to the Anshan's Han population,followed by populations from Henan,Heilongjiang,Jilin,Shandong,and Chongqing.Furthermore,the genetic distances between the Han population in Dalian and the Qiang population in Beichuan or the Miao population in Guizhou were relatively closer than that to the Manchu population living in Liaoning.Conclusion The genetic distance between the Han population in Dalian and other groups is not entirely proportional to ethnicities and geographical proximity.Both population migration and ethnic assimilation or isolation may have influence on it.
