Pathogenic and epidemiological characteristics of 507 cases of human brucellosis in Shaanxi Province from 2014 to 2021
10.3760/cma.j.cn231583-20220926-00327
- VernacularTitle:2014 - 2021年陕西省507例人间布鲁氏菌病病例的病原及流行病学特征分析
- Author:
Shoumin NIE
1
;
Boyan LUO
;
Wenjing WANG
;
Dijia ZHOU
;
Suoping FAN
;
Cuihong AN
;
Yangxin SUN
Author Information
1. 陕西省疾病预防控制中心鼠疫与布鲁氏菌病防控所，西安 710054
- Keywords:
Brucellosis;
Etiological culture;
Epidemiological characteristics
- From:
Chinese Journal of Endemiology
2023;42(12):979-983
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the pathogenic and epidemiological characteristics of human brucellosis in Shaanxi Province, and to provide a basis for scientific prevention and control of human brucellosis in Shaanxi Province.Methods:The pathogenic culture data of 507 reported cases of human brucellosis reported in Shaanxi Province from 2014 to 2021 were collected from the Shaanxi Provincial Center for Disease Control and Prevention. The epidemiological data of the cases were collected from the Infectious Disease Information Reporting Management System of China Disease Prevention and Control Information System. The data were summarized and analyzed using Excel 2016 software, and visualized using ArcGIS 10.6 software.Results:The 507 cases were concentrated from 2018 to 2021 (322 cases), with a peak incidence period from May to July (255 cases). Cases mainly distributed in Weinan City (129 cases), Yulin City (114 cases) and Yan'an City (97 cases). Farmers were the main occupation (415 cases). The cases were mainly aged 40 - 59 (272 cases). The male to female gender ratio was 3.22 ∶ 1.00 (387 ∶ 120). Totally 95.46% (484/507) of the cases had a history of close contact with cattle or sheep, mainly sheep (480 cases). The clinical symptoms included fever, fatigue, hyperhidrosis, joint and muscle pain, with rare liver, spleen and testicular enlargement. Totally 89.55% (454/507) of the cases were diagnosed during the acute phase. In vitro agglutination test, 1 ∶ 200 positive cases were the most common (139 cases). Totally 214 strains of Brucella were isolated and cultured, and the rate of bacterial production was 42.21%, all of which were Brucella melitensis, of which type 3 accounted for 79.91% (171/214). Conclusion:Human brucellosis cases in Shaanxi Province are mainly infected by contact with sheep, with the main source of infection being Brucella melitensis type 3.
