Analysis of the Use of Sacubitril/valsartan in 2 682 Patients During Hospitalization

VernacularTitle:2 682例次服用沙库巴曲缬沙坦患者住院期间用药分析
Author: Xinrui CAO ¹ ; Ruobin ZHANG ; Ziqiu LIU ; Simin YAN ; Weihong GE
Author Information

1. 南京中医药大学鼓楼临床医学院,南京鼓楼医院药学部,南京 210029
Keywords: Sacubitril/valsartan; Drug analysis; Inpatient
From: Herald of Medicine 2024;43(3):457-463
CountryChina
Language:Chinese
Abstract: Objective To retrospective analyze the use of inpatients taking sacubitril/valsartan in Nanjing Drum Tower Hospital,and to provide references for rational clinical application.Methods The relevant data of inpatients taking sacubitril/valsartan in our hospital were systematically collected from July 2019 to September 2021,and the rationality of drug use was eval-uated.Results A total of 2 682 cases were collected,and 868 cases(32.36%)of them involved 918 times of irrational drug use.The specific situations of irrational drug use included off-label use(182 times),irrational usage and dosage(389 times),irrational conversation of drugs(251 times),and irrational drug use for special populations(96 times).Conclusion The use of sacubitril/valsartan exists in unreasonable situations in our hospital.Clinical pharmacists should participate in medication man-agement to a certain extent,strengthen the pharmaceutical care of patients,and improve the rational rate of drug use.