Clinical Comprehensive Evaluation of Oral Anticoagulants Based on A Quick Guideline for Drug Evaluation and Selection in Chinese Medical Institutions(the Second Edition)
10.3870/j.issn.1004-0781.2024.02.020
- VernacularTitle:基于《中国医疗机构药品评价与遴选快速指南(第二版)》的口服抗凝药物临床综合评价
- Author:
Dongdong TIAN
1
;
Gexi CAO
;
Chaojun XUE
;
Zhanjun DONG
;
Jianping LIU
;
Zhigang ZHAO
Author Information
1. 河北省人民医院药学部,石家庄 050051
- Keywords:
Oral anticoagulants;
Warfarin;
Dabigatran;
Rivaroxaban;
Edoxaban;
Apixaban;
Selection evaluation;
Digital scoring
- From:
Herald of Medicine
2024;43(2):274-282
- CountryChina
- Language:Chinese
-
Abstract:
Objective A comprehensive evaluation of oral anticoagulants(OACs)was conducted using the A Quick Guideline for Drug Evaluation and Selection in Chinese Medical Institutions(the Second Edition),to provide a reference for drug selection and clinical medication decisions in medical institutions.Methods Evaluation evidence was collected,and the drugs included in the evaluation were quantified on four dimensions of clinical properties(efficiency and safety),pharmaceutical properties,economy and others.Results All oral anticoagulants included in the evaluation had a score of 70 or higher in the comprehensive evaluation,while warfarin had the highest overall score.Clinical properties and pharmacologic properties were identified as the core attributes for drug selection evaluation.When considering only these factors,edoxaban received the highest score.Conclusion OACs are the preferred option for patients requiring long-term anticoagulation therapy.Various OACs offer distinct clinical advantages.Utilizing the Guidelines(Second Edition)for oral anticoagulant selection and evaluation can offer visual evidence for drug selection and promote the scientific,rational,and safe use of drugs in clinical management.
