Research Progress on the Use of Phytoestrogens in the Prevention and Treatment of Alzheimer's Disease
10.3870/j.issn.1004-0781.2024.02.016
- VernacularTitle:植物雌激素防治阿尔茨海默病的研究进展
- Author:
Xuri SHEN
1
;
Fuwang LIU
;
Yanman LIU
;
Jiarui DU
;
Xueqin HOU
Author Information
1. 山东第一医科大学(山东省医学科学院)药学院,泰安 271016
- Keywords:
Phytoestrogen;
Estrogen receptor;
Alzheimer's disease
- From:
Herald of Medicine
2024;43(2):248-254
- CountryChina
- Language:Chinese
-
Abstract:
Phytoestrogens refer to a class of compounds in plants that can bind to and activate estrogen receptors in mammalian organisms,exerting varying degrees of protective and improvement effects on the body.Modern pharmacological studies have found that phytoestrogens have therapeutic effects on the cardiovascular system,nervous system,endocrine system,immune system,and so on.It is worth noting that the binding of phytoestrogens to estrogen receptors in the brain can produce central neuroprotective effects and improve learning and cognitive impairment in Alzheimer's pectients through multiple targeted pathways.This paper describes the research progress and related mechanisms of phytoestrogen-like monomers,Chinese herbal medicine,and compound formulations in Alzheimer's disease.The aim is to provide new drug design ideas and solutions for the effective treatment of senile dementia with traditional Chinese medicine.
