GC Fingerprint and Multi-component Content Determination of Xiangsha Yangwei
10.3870/j.issn.1004-0781.2024.01.018
- VernacularTitle:香砂养胃丸气相色谱指纹图谱及多成分的含量测定
- Author:
Yiqing MAO
1
;
Liqing TONG
;
Ying ZHU
;
Qing ZHANG
;
Wenting LIU
;
Yu CAO
Author Information
1. 南京市食品药品监督检验院,南京 211198
- Keywords:
Xiangsha Yangwei pill;
Gas chromatography;
Fingerprint;
Content determination
- From:
Herald of Medicine
2024;43(1):115-121
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish the method of fingerprint and content determination of multi-component for Xiangsha Yangwei pill by gas chromatography(GC).Methods The GC fingerprint of Xiangsha Yangwei pill was found,and the peak attribution was carried out.The contents of limonene,eucalyptol,camphor,borneol,bornyl acetate,patchouli alcohol,pogostone,and α-cyperone were determined.Results The fingerprint similarity of 56 batches of Xiangsha Yangwei pill were 0.33-0.99,28 common peaks were confirmed,and 14 known components were identified.Limonene,eucalyptol,camphor,borneol,bornyl acetate,patchouli alcohol,pogostone and α-cyperone showed good linearity within the determined ranges(14.30-286.08,24.52-490.44,16.14-322.88,9.40-187.95,15.39-307.83,25.78-515.60,19.95-398.90,and 24.87-497.30 μg·mL-1).The average recoveries were 101.20％,97.90％,93.97％,94.23％,102.94％,100.54％,99.16％,and 98.31％;with the RSDs were 2.41％,1.48％,1.65％,2.00％,1.93％,2.30％,2.07％,and 2.38％,respectively.The concentrations of eight components were 0.2-959.1,0.3-420.4,1.0-542.6,0.0-64.5,0.0-364.2,0.0-339.6,0.0-130.7,0.0-82.0 μg·g-1,respectively.Conclusion The fingerprint and multi-component determination method can be used for the quality control and evaluation of Xiangsha Yangwei pill.
