Pharmacological Effects of Icariin on Male Reproductive System:A Review and Literature Visualization
10.3870/j.issn.1004-0781.2024.01.016
- VernacularTitle:淫羊藿苷对男性生殖系统的药理作用研究进展及文献可视化分析
- Author:
Jingyi ZHANG
1
;
Junjun LI
;
Chunyan FANG
;
Shiyun PU
;
Feng ZHANG
;
Aili YANG
;
Xujun YU
Author Information
1. 成都中医药大学临床医学院,成都 610075
- Keywords:
Icariin;
Male reproductive system;
Signal pathway;
Molecular mechanism;
Bibliometrics;
Visualization
- From:
Herald of Medicine
2024;43(1):96-105
- CountryChina
- Language:Chinese
-
Abstract:
Icariin,which belongs to the class of flavonoids,is the main active ingredient of the traditional tonic Chinese herb Epimedii Folium.Modern studies have shown that icariin has a wide range of effects on the male reproductive system.It has various pharmacological activities such as regulating cell proliferation and apoptosis,antioxidants,promoting testosterone secretion,improving erectile function,inhibiting prostate cancer cell migration,invasion,and regulating cell cycle.It has research value and application prospects in the field of urology and assisted reproduction.Therefore,Icariin's pharmacological effects and molecular mechanisms on the male reproductive system are reviewed in this paper combined with literature visualization analysis.It is expected to provide a theoretical basis for the therapeutic value development and application of icariin in male reproductive health.
