Research Progress on the Effect of Abnormal Thyroid Function on the Coagulation System and the Interaction of Therapeutic Drugs
10.3870/j.issn.1004-0781.2024.01.014
- VernacularTitle:甲状腺功能异常对凝血系统的影响及治疗药物相互作用研究进展
- Author:
Min JIANG
1
;
Yuan BIAN
;
Enwu LONG
Author Information
1. 四川大学华西公共卫生学院/四川大学华西第四医院药剂科,成都 610041
- Keywords:
Hyperthyroidism;
Hypothyroidism;
Antithyroid agents;
Thyroxine;
Anticoagulants;
Coagulants;
Drug interactions;
Coagulation system
- From:
Herald of Medicine
2024;43(1):85-90
- CountryChina
- Language:Chinese
-
Abstract:
For patients with abnormal thyroid function,the detection of peripheral blood coagulation indicators may be irregular,and there is a potential risk of thrombosis or bleeding.Patients with hyperthyroidism have significant endothelial dysfunction and risk of thrombosis.However,the reports on the effect of hypothyroidism on coagulation function are still controversial.The potential risk of abnormal thyroid function to the coagulation system may interfere with the safety of anticoagulant therapy,and the interaction between thyroid disease treatment drugs and anticoagulant drugs also affects the safety of the patient's medication.Therefore,this article is based on previous research literature,analyzes the correlation between abnormal thyroid function and coagulation function,and evaluates and discusses the impact of abnormal thyroid function on the coagulation system and related therapeutic drug interactions.It is expected to provide a reference for diagnosing and treating patients with thyroid dysfunction and abnormal coagulation function.
