Study of labor Process Management and Perinatal Outcome in Pregnant Women Colonized with Group B Streptococcus
10.11969/j.issn.1673-548X.2024.01.027
- VernacularTitle:B族链球菌定植产妇的产程管理与围生结局的研究
- Author:
Lulu CHEN
1
;
Fan WANG
Author Information
1. 325027 温州医科大学附属第二医院、育英儿童医院产科
- Keywords:
Group B streptococcus;
Labor process management;
Duration of rupture of membranes;
Maternal and infant infection
- From:
Journal of Medical Research
2024;53(1):136-141
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the labor process management and perinatal outcome in full-term pregnant women colonized with group B streptococcus.Methods The clinical data of 355 full-term pregnant women with positive GBS screening(the positive GBS group)and 355 full-term pregnant women with negative GBS screening(the negative GBS group)from October 2020 to November 2021,in the department of obstetrics and gynecology of the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical Uni-versity were collected.The labor characteristics,duration of rupture of membranes and perinatal outcome were compared between the two groups.Results In the positive GBS group,the incidences of intrapartum fever,postpartum fever,hospital stays,histological chorioam-nionitis,neonatal admission to neonatal intensive care unit(NICU),and neonatal sepsis were higher than those in the negative GBS group(P＜0.05).There was no significant difference between the two groups with mode of initiation of labor,mode of delivery,premature rup-ture of membrane,clinical chorioamnionitis,duration of rupture of membranes,the first stage of labor,the active stage,the second stage of labor,birth weight of newborn,gender of newborn,fetal distress,and neonatal jaundice(P＞0.05).According to the difference of in-terval between rupture of the fetal membranes,the positive GBS group was divided into three groups:＜12 hours group,≥12 and＜24 hours group,and ≥ 24 hours group.The＜12 hours group was selected as the control group.In the ≥ 12 and＜24 hours group,the first stage of labor,active stage,second stage of labor,and hospital stay were longer than those in the control group.The incidence of prema-ture rupture of membranes of term and forceps delivery was higher than that in the control group(P＜0.05).In the ≥ 24 hours group,the first stage of labor,second stage of labor,and hospital stay were longer than those in the control group.The incidence of premature rup-ture of membranes of term,intrapartum fever,postpartum fever,histological chorioamnionitis,and cesarean section was higher than that in the control group(P＜0.05).In the GBS positive group,there was no significant difference between neonatal sepsis and neonatal no-sepsis of mode of initiation of labor,mode of delivery,type of rupture of membranes,histological chorioamnionitis,duration of rupture of membranes,and duration of labor(P＞0.05).Conclusion The labor process is not affected by GBS.However,GBS increases the risk of maternal and infant infection.The full-term women colonized with group B streptococcus delivery within 24 hours after rupture of membranes,which can shorten labor,reduce labor complications,and improve adverse perinatal outcomes.
