Analysis of Related Characteristics of Cerebral Infarction Patients with Hyperhomocysteinemia
10.11969/j.issn.1673-548X.2024.01.010
- VernacularTitle:高同型半胱氨酸血症脑梗死患者的相关特征分析
- Author:
Yihong SHI
1
;
Jing LI
;
Min WANG
Author Information
1. 300193 天津中医药大学第一附属医院、国家中医针灸临床医学研究中心
- Keywords:
Cerebral infarction;
Hyperhomocysteinemia;
Folate deficiency
- From:
Journal of Medical Research
2024;53(1):41-44
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the common symptoms and associated disease characteristics of hyperhomocysteinemia in cere-bral infarction patients and the correlation analysis of influencing factors.Methods A total of 151 participants with blood homocysteine≥15μmol/L and 86 participants with blood homocysteine＜15μmol/L were identified as the hyperhomocysteinemia with cerebral infarction group(H group)and the normal cerebral infarction group(N group),respectively.The symptoms and influence factors in the two groups were compared.Results Among cerebral infarction patients,patients in H group were older(P=0.049),more male(P=0.002),had a history of smoking(P=0.025),diabetes(P=0.008),hyperlipidemia(P=0.034),folate deficiency(P=0.002)and associated cognitive impairment(P=0.009)and language barrier(P=0.043).Binary Logistic regression analysis showed that age(P=0.023),diabetes(P=0.018),folate deficiency(P=0.026),and cognitive impairment(P=0.019)were independent related factors of in-creased blood homocysteine level.Conclusion Cerebral infarction patients with hyperhomocysteinemia are elderly,and most of them have diabetes,folate deficiency,and cognitive impairment.
