Multicenter retrospective investigation and analysis of the rationality of the application of human albumin in cardiac surgery during the perioperative period
10.12173/j.issn.1005-0698.202305040
- VernacularTitle:人血白蛋白心外科围手术期应用合理性多中心回顾性调查分析
- Author:
Wenfei PAN
1
;
Huan YU
;
Dasheng DANG
;
Lijuan CHEN
;
Te LI
;
Tianlu SHI
;
Banghua HUANG
;
Boxia LI
;
Xiaoxue GONG
;
Ying WANG
Author Information
1. 中国医学科学院阜外医院药剂科(北京 100037)
- Keywords:
Human serum albumin;
Clinical application;
Retrospective study;
Rational drug use
- From:
Chinese Journal of Pharmacoepidemiology
2024;33(2):176-183
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical application of perioperative human serum albumin(HSA)in cardiac surgery in multiple regions in China,and to evaluate the rationality of its clinical application in conjunction with the clinical guidelines,in order to provide a reference for promoting the rational application of HSA.Methods The medical records of patients who underwent cardiac surgery from April to June 2019 in eight hospitals across the country were retrospectively collected.The statistical information on patients'general information,the dosage,course of treatment,and cost of HSA,and the serum albumin level before and after medication was analyzed to evaluate the use of HSA.Relevant evaluation criteria were established,and the rationality of its medication was evaluated.Results Data from a total of 449 patients were included for analysis,the appropriate rate of medication was 81.1％.The course of medication was mostly＞2-5 days and the total amount of HSA was mostly 50-99 g.The main purpose of medicaiton were improving colloid osmotic pressure,reducing exudation to improve interstitial edema,postoperative volume expansion.Conclusion Clinical attention should be paid to ensure the rational application of HSA in cardiac surgery during the perioperative period and prevent the abuse of blood products.
