Establishment and application of drug use evaluation criteria of fibrinogenase for injection
10.12173/j.issn.1005-0698.202306025
- VernacularTitle:注射用纤溶酶药物利用评价标准的建立与应用
- Author:
Ruiqin REN
1
;
Jing ZHANG
;
Yizhen GONG
;
Jinhua ZHANG
Author Information
1. 福建省宁德市中医院药剂科(福建宁德 352100)
- Keywords:
Fibrinogenase for injection;
Drug use evaluation;
Standard;
Expert consultation;
Rational drug use
- From:
Chinese Journal of Pharmacoepidemiology
2024;33(2):145-151
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish the drug use evaluation(DUE)standard of fibrinogenase for injection and provide a reference for the rational clinical application of fibrinogenase for injection.Methods Based on the specification of fibrinogenase for injection,the DUE standard was established from three aspects:drug indication,drug process and drug results,with reference to relevant guidelines and literature,and through discussion with clinical experts.A retrospective survey was conducted to evaluate the inpatients using fibrinogenase for injection from January 2021 to December 2021 in Ningde Hospital of Traditional Chinese Medicine,Fujian Province.Results A total of 256 patients were included,with a medication reasonable rate of 61.72％.The irrational use of drugs was mainly including the inappropriate usage and dosage(3.91％),off-label medication(1.95％),no skin test(8.98％),too long or inadequate course of medication(25.00％).Conclusion The DUE standard established of fibrinogenase for injection is scientific,practical and feasible.The use of fibrinogenase for injection in contraindications and high blood coagulation state,and off-label medication can be further optimized.
