Drug use evaluation of ozagrel sodium based on weighted TOPSIS method
10.12173/j.issn.1005-0698.202306022
- VernacularTitle:基于加权TOPSIS法的奥扎格雷钠药物利用评价
- Author:
Shanshan ZHU
1
;
Na WANG
;
Huiya CAI
;
Jinhua ZHANG
Author Information
1. 河南省直第三人民医院药剂科(郑州 450000)
- Keywords:
Ozagrel sodium;
Drug use evaluation;
Weighted TOPSIS method;
Delphi method;
Rational drug use
- From:
Chinese Journal of Pharmacoepidemiology
2024;33(2):137-144
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish evaluation of ozagrel sodium by weighted TOPSIS method so as to provide a reference for improving the rational use of ozagrel sodium.Methods Based on the drug instructions,guidelines,relevant literatures and Delphi method,the evaluation criteria for the clinical rationality of ozagrel sodium were formulated.Attribute hierarchical model(AHM)was used to assign weights to the indicators,the weighted TOPSIS method was employed to analyze and evaluate the rationality of 108 patients that discharged from the Third People's Hospital of Henan Province from January 2021 to April 2022.Results The reponse rates of two rounds of expert advice questionnaires were 100％,the authoritative coefficients(Cr)were 0.85,0.83(＞0.70),and the experts fully affirmed the items of the standard.Among the 108 cases evaluated,37 cases(34.26％)were judged to be reasonable,52 cases(48.15％)were judged to be basically reasonable and 19 cases(17.59％)were judged to be unreasonable.The main unreasonable problems were manifested in indications,the timing of administration,drug course and monitoring of efficacy and laboratory parameters.Conclusion The method of DUE of ozagrel sodium based on weighted TOPSIS is more comprehensively and intuitively.The application of ozagrel sodium in the hospital is relatively standardized,but there are problems in the course of medication,indications,and timing of administration.So it is necessary to promote the rational use by strengthening the cooperation between pharmacists and physicians,and improving pharmaceutical intervention.
