Establishment and application of drug use evaluation criteria of argatroban
10.12173/j.issn.1005-0698.202312013
- VernacularTitle:阿加曲班药物利用评价标准的建立与应用
- Author:
Hengfen DAI
1
;
Caiyun ZHENG
;
Yunchun LIU
;
Hong ZHANG
;
Maobai LIU
;
Jinghua ZHANG
Author Information
1. 福建医科大学附属福州市第一医院药学部(福州 350009)
- Keywords:
Argatroban;
Drug use evaluation criteria;
Expert consultation method;
Rational drug use
- From:
Chinese Journal of Pharmacoepidemiology
2024;33(2):121-127
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish the argatroban drug use evaluation(DUE)criteria and provide reference for the rational use of argatroban in clinical practice.Methods Based on the domestic and foreign drug instructions of argatroban,referring to relevant guidelines and literature,the DUE standard rules were established by expert consultation.Using the established standard rules,the medical records of argatroban in the Fuzhou First Hospital Affiliated with Fujian Medical University from August 2020 to August 2022 were evaluated for the rationality of medication.Results A total of 368 medical records were included,the rational rate of drug use was 48.64％,and the irrational drug use was mainly without indications(46.19％)and inappropriate combination of drugs(4.35％).Conclusion The rational rate of argatroban clinical use in the hospital is not high,and the problems mainly include off-indication drug use and unreasonable combination drug use.Through the establishment and clinical application of DUE standard rules,the clinical use of argatroban can be further standardized and the ability of rational drug use can be improved.
