The effect of standard channel ultrasonography-pneumatic lithotripsy on kidney function and prognosis of patients in the treatment of complex kidney calculi
10.3760/cma.j.cn115455-20220106-00014
- VernacularTitle:标准通道超声-气压弹道碎石术治疗复杂肾结石对患者肾功能及预后的影响研究
- Author:
Xiong ZHAO
1
;
Fawu YANG
Author Information
1. 安徽省濉溪县医院泌尿外科，淮北 235100
- Keywords:
Lithotripsy;
Kidney calculi;
Postoperative complications;
Prognosis
- From:
Chinese Journal of Postgraduates of Medicine
2023;46(10):905-909
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effect of standard channel ultrasonography-pneumatic lithotripsy on kidney function and prognosis of patients in the treatment of complex kidney calculi.Methods:A total of 60 patients with complex kidney calculi admitted to Suixi County Hospital of Anhui Province from October 2017 to September 2020 were selected and divided into the observation group (29 cases, received ultrasound-pneumatic lithotripsy operation) and the control group (31 cases, received pneumatic lithotripsy operation) according to different treatment methods. The perioperative indexes, stone clearing rate, recurrence rate, complication rate, the renal function changes and quality of life(QOL) changes before and after the operation were compared between the two groups.Results:The operation time, intraoperative blood loss, postoperative decrease in hemoglobin(Hb), postoperative hematuria time and times of postoperative using analgesic in the observation group were lower than those in the control group: (80.86 ± 16.95) min vs. (94.31 ± 13.11) min, (60.52 ± 9.17) ml vs. (69.34 ± 10.06) ml, (8.58 ± 2.05) g/L vs. (10.11 ± 2.42) g/L, (3.02 ± 1.09) d vs. (3.65 ± 1.27) d, (4.59 ± 1.62) times vs. (6.43 ± 1.39) times, there were statistical differences ( P<0.05). At 4 weeks post operation, the levels of renal function indexes urinary N-acetyl-glucosaminidase (NAG), urinary β2 microglobulin (β2-MG), serum neutrophilic gelatinase-associated apolipoprotein (NGAL), serum creatinine (SCr) in the observation group were lower than those in the control group: (5.13 ± 2.14) U/L vs. (7.08 ± 2.35) U/L, (0.14 ± 0.07) mg/L vs. (0.22 ± 0.09) mg/L, (2.06 ± 1.01) μg/L vs. (2.71 ± 1.06) μg/L, (97.05 ± 20.97) μmol/L vs. (110.64 ± 20.32) μmol/L, there were statistical differences ( P<0.05). The clearing stone rate in the observation group was higher than that in the control group, and recurrence rate was lower than that in the control group: 93.10%(27/29) vs. 70.97%(22/31), 0 vs. 19.35%(6/31), there were statistical differences ( χ2 = 4.90, 4.27, P<0.05).The incidence of complication in the two groups had no significant difference ( P>0.05). The length of stay in the observation group was shorter than that in the control group: (5.54 ± 2.06) d vs. (7.01 ± 2.13) d; the scores of QOL at 3 and 6 months after operation in the observation group were higher than those in the control group: (82.55 ± 6.36) scores vs. (78.98 ± 5.32) scores, (87.03 ± 7.21) scores vs. (83.46 ± 6.05) scores, there were statistical differences ( P<0.05). Conclusions:Standard channel ultrasonography-pneumatic lithotripsy can effectively treat patients with complex kidney stones, improve renal function and promote surgical recovery. Its safety is guaranteed to some extent.
