Diagnosis and treatment of primary intraspinal paraganglioma
10.3760/cma.j.cn115455-20230301-00194
- VernacularTitle:原发性椎管内副神经节瘤的诊断和治疗
- Author:
Shaorong HU
1
;
Peng PENG
;
Feng CHEN
;
Xiangyang WANG
;
Mengqi XU
;
Jingwen LI
Author Information
1. 襄阳市中心医院神经外科，襄阳 441000
- Keywords:
Spinal canal;
Paraganglioma;
Diagnosis;
Microsurgery
- From:
Chinese Journal of Postgraduates of Medicine
2023;46(9):844-849
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To provide a basis for its diagnosis and treatment for clinicians by analyzing the clinical manifestations, imaging features and surgical efficacy of primary intraspinal paraganglioma.Methods:The clinical data of 6 patients with intraspinal paraganglioma from April 2014 to January 2021 in Xiangyang Central Hospital were retrospectively analyzed, and all patients were treated with microsurgery via a posterior median approach.Results:All 6 patients achieved total tumor resection, and the postoperative pathological diagnosis was paraganglioma. Among them, 1 patient′s tumor located inside and outside the cervical spinal canal without destruction of the vertebral body; 1 patient′s tumor located lumbosacral canal with destruction of the vertebral body; the others 4 patients′ tumor located within the lumbar spinal canal. The patients were followed up for 12 to 120 months after surgery, with a median follow-up time of 61.5 months. MRI examination was performed at the last follow-up, and no recurrence was observed. The patients underwent MRI examination at the last follow-up, and none of the patients recurred.Conclusions:The intraspinal paraganglioma is a rare tumor, and nonfunctional benign tumors are predominant. Its clinical and imaging manifestations lack specificity and are often difficult to diagnose before surgery. Surgical resection, especially complete resection, has a better prognosis, and the effectiveness of adjuvant therapy is uncertain.
