A Case of Rheumatoid Arthritis with Chronic Eosinophilic Pneumonia Associated with Eosinophilic Pleural Effusion.
10.4078/jrd.2013.20.5.328
- Author:
Yong Gwan JEE
1
;
Sang Ho RA
;
Yu Mi PARK
;
Jae Whang CHA
;
Yong Seok KANG
;
Jeong Ha PARK
;
Tae Young KANG
Author Information
1. Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea. jhpark10@yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
Rheumatoid arthritis;
Chronic eosinophilic pneumonia;
Pleural effusion
- MeSH:
Antirheumatic Agents;
Arthritis, Rheumatoid*;
Eosinophilia;
Eosinophils*;
Exudates and Transudates;
Glucose;
Humans;
Hydrogen-Ion Concentration;
Lung;
Middle Aged;
Oxidoreductases;
Pleural Effusion*;
Pulmonary Eosinophilia*;
Steroids;
Thorax
- From:Journal of Rheumatic Diseases
2013;20(5):328-331
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We describe a 48-year-old man with family history of rheumatoid arthritis (RA) affected by chronic eosinophilic pneumonia (CEP) with severe peripheral eosinophilia. CEP might develop as a complication of longstanding active RA. The patient with 5 months history of seropositive RA and chronic respiratory symptoms, alveolar and blood eosinophilia, peripheral pulmonary infiltrates and pleural effusion on chest imaging. The lung may be involved as an extraarticular manifestation of RA. However, CEP is not recognized as a typical lung manifestation of RA, and the two diseases rarely coexist. The effusion was an eosinophil predominant exudates and was characterized by low pH, and glucose level and high lactic dehydrogenase. The patient responded rapidly to combination of steroids and disease modifying anti-rheumatic drugs.