Regulatory effect of autonomic nerve on aqueous humor outflow pathway

VernacularTitle:自主神经对房水流出通道的调控作用
Author: Jialing HAN ^{1
,

2} ; Lijuan XU ; Xiaorui GANG ; Tao ZHOU ; Yuanbo LIANG
Author Information

1. 325027 浙江省温州市,温州医科大学附属眼视光医院
2. 325027 浙江省温州市,温州医科大学青光眼研究所
Keywords: autonomic nerve; glaucoma; aqueous humor outflow pathway; intraocular pressure
From: Recent Advances in Ophthalmology 2024;44(1):62-65
CountryChina
Language:Chinese
Abstract: Glaucoma is the leading irreversible blinding eye disease worldwide,and intraocular pressure(IOP)plays a key role in the occurrence and development of glaucoma.However,the underlying IOP regulatory mechanism remains un-clear.Currently,clinical IOP-lowering drugs work either by reducing aqueous humor formation or increasing aqueous hu-mor outflow with limited reduction amplitude.Recent studies demonstrate that IOP may be regulated by autonomic nerves.To understand the distribution and regulatory mechanism of autonomic nerves in the aqueous humor outflow pathway and provide new ideas for IOP-lowering study and novel drug exploration,we review the roles of the autonomic nervous system in the formation and outflow of aqueous humor in this article.