Influencing factors of coronary heart disease in advanced aged population and therapeutic effect of PCI
10.3969/j.issn.1008-0074.2023.06.04
- VernacularTitle:高龄人群发生冠心病的影响因素及PCI术的疗效分析
- Author:
Yu SHEN
1
;
Xue-Mei YANG
;
Lu YANG
;
Gui-Ying YOU
Author Information
1. 四川大学华西医院心脏内科,四川 成都 610041
- Keywords:
Coronary disease;
Cholesterol,HDL;
Uric acid
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2023;32(6):564-569
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze influencing factors of coronary heart disease(CHD)in advanced aged population and the therapeutic effect of percutaneous coronary intervention(PCI).Methods:According to diagnosed as CHD or not,a total of 209 aged patients underwent cardio-and cerebrovascular examination in our hospital were divided into CHD group(n=104)and no CHD group(n=105),and general clinical data were compared between two groups.According to treatment method,CHD group was divided into routine treatment group(received routine medication)and PCI group;and recovery time,hospital stay,incidence rate of adverse events during admission and prognosis within one-year follow-up were compared between two groups.Influencing factors of CHD in aged population was analyzed.Results:Compared with no CHD group,there were significant rise in percentages of age>80 years,smoking,diabetes mellitus,hypertension,total cholesterol>5.17mmol/L,triglyceride>1.7mmol/L,high density lipoprotein cholesterol(HDL-C)<0.96mmol/L,low density lipoprotein cholesterol>3.37mmol/L,uric acid>420μmol/L and fibrinogen>4 g/L in CHD group(P<0.05 or<0.01).Compared with routine treat-ment group,there were significant reductions in recovery time,hospital stay,incidence rates of adverse events,lu-men loss/restenosis,primary and secondary endpoint events within one-year follow-up in PCI group(P<0.05 or<0.01).Binary Logistic regression analysis indicated that age>80 years,uric acid>420μmol/L and HDL-C<0.96mmol/L were independent risk factors for CHD in advanced aged population(OR=1.755~6.103,P<0.05 or<0.01).Conclusion:Age>80 years,uric acid>420μmol/L and HDL-C<0.96 mmol/L are independent risk fac-tors for coronary heart disease in advanced aged population.PCI can significantly shorten recovery time and treat-ment time in advanced aged patients with coronary heart disease with good safety.