Research progress on endothelial molecular pathogenesis in sepsis-induced coagulopathy
10.3760/cma.j.issn.1673-4912.2024.02.011
- VernacularTitle:脓毒症凝血病内皮分子机制的研究进展
- Author:
Juanzhen LI
1
;
Nuerjiamali ZEMIN
;
Long XIANG
Author Information
1. 上海交通大学医学院附属上海儿童医学中心重症医学科 200127
- Keywords:
Sepsis;
Sepsis-induced coagulopathy;
Disseminated intravascular coagulation;
Disseminated intravascular microthrombosis;
Endotheliopathy;
Complement activa
- From:
Chinese Pediatric Emergency Medicine
2024;31(2):136-140
- CountryChina
- Language:Chinese
-
Abstract:
The diagnosis and treatment of sepsis-induced coagulopathy（SIC）and disseminated intravascular coagulation（DIC）are very difficult in clinical practice.It also increases the mortality of sepsis in children.This article reviewed the latest pathophysiological mechanism of endothelial molecular in the occurrence and development of SIC and DIC in sepsis，so as to provide new theoretical basis for the clinical treatment of SIC and DIC in sepsis.
