Research progress on T lymphocyte subsets in immunosuppression of sepsis in children
10.3760/cma.j.issn.1673-4912.2024.01.011
- VernacularTitle:T淋巴细胞亚群在儿童脓毒症免疫抑制中的作用
- Author:
Xue LIU
1
;
Zhiyuan WANG
;
Peng SHEN
;
Shujun LI
Author Information
1. 新乡医学院第一附属医院儿童重症监护室，卫辉 453100
- Keywords:
Immunosuppression;
T lymphocyte subsets;
Sepsis;
Children
- From:
Chinese Pediatric Emergency Medicine
2024;31(1):57-61
- CountryChina
- Language:Chinese
-
Abstract:
Although a great deal of research has been done on sepsis in children，its pathogenesis remains controversial and unresolved，one of which is immune dysfunction.Immunosuppression is the core part of immune dysfunction，and it is related to the disease progression，treatment options，and prognosis changes in patients with sepsis.Since T lymphocytes play a crucial role in immune function，they have been regarded as an important indicator for judging changes in immune function in clinical practice.This review explained the mechanism of immunosuppression caused by some T lymphocyte subsets and its clinical application value in the evaluation，prognosis and immune intervention of sepsis.
