Hormone therapy for tuberculous meningitis patient with history of hormone allergy
10.3969/j.issn.1671-332X.2024.03.042
- VernacularTitle:伴激素过敏史的结核性脑膜炎患者的激素治疗策略探讨
- Author:
Xiaowen ZHOU
1
;
Meichen ZHOU
;
Wanmei WU
;
Honglan ZHONG
Author Information
1. 广州市胸科医院 广东广州 510095
- Keywords:
Tuberculous meningitis;
Methylprednisolone;
Allergy
- From:
Modern Hospital
2024;24(3):490-492
- CountryChina
- Language:Chinese
-
Abstract:
Objective The aim is to provide drug regimen for patients who have hormone allergy history but need hor-mone therapy.Methods Pharmacists analyzed the sensitization mechanism of methylprednone in combination with insturction and literature,assisted clinicians to formulate oral hormone therapy for tuberculosis meningitis with history of menthylprednisolone and verified the effectiveness and safety of the drug regimen.Results Methylprednisolone injection contains trace amount of milk protein and should not be used in patients with definite allergy to cow's milk.After changing to oral hormone therapy,the patient did not appear allergic again,and the condition was stable.Conclusion Gucocorticoids can also induce allergic reactions,so patients'previous allergic history should be paid attention in the process of medical history collection.Meanwhile,pharmacists can also give full play to their pharmaceutical expertise to assist clinicians in formulating individualized drug administration plans to ensure the effectiveness and safety of patients.