A comparative study of drug treatment effect of anterior wall STEMI with heart failure after primary PCI
10.3969/j.issn.1671-332X.2024.03.039
- VernacularTitle:前壁STEMI直接PCI后伴心力衰竭的药物治疗疗效对比研究
- Author:
Zhangyu CHEN
1
;
Zhiguang ZHANG
;
Dipei CHEN
Author Information
1. 云浮市人民医院 广东云浮 527300
- Keywords:
Acute anterior wall st-segment elevation myocardial infarction;
Primary percutaneous coronary intervention;
Heart failure;
Furosemide;
Nitroglycerin;
Neoactivin;
Dopamine
- From:
Modern Hospital
2024;24(3):479-481,485
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the therapeutic impact of acute anterior wall ST-segment elevation myocardial infarc-tion(STEMI)and primary percutaneous coronary intervention(PCI)in patients with heart failure.Methods 90 patients with anterior wall STEMI with heart failure after primary PCI were selected from the cardiovascular Department of Yunfu People's Hos-pital from July 2021 to June 2023,and they were split into three groups using the random number expression approach,each group containing 30 examples.Group A was treated with furosemide+nitroglycerin,group B was treated with furosemide+nitro-glycerin+neoactin,and group C was treated with furosemide+nitroglycerin+dopamine.The clinical efficacy,cardiac function[left ventricular end-systolic diameter(LVESD),left ventricular end-diastolic diameter(LVEDD),left ventricular ejection frac-tion(LVEF),amino terminal B-type natriuretic peptide precursor(NT-ProBNP)]and clinical indexes of the three groups after treatment were compared.Results ①There was significant difference in total treatment rate among the three groups(P＜0.05).Group B and C had significantly greater total effective rates than group A.(P＜0.05).②After 3 days of treatment,the levels of LVEF in the three groups were increased(P＞0.05),while the levels of NT-ProBNP,LVESD and LVEDD were decreased,and the levels of NT-ProBNP,LVESD and LVEDD in group B and C were lower than those in group A(all P＜0.05).③The length of hospital stay and readmission rate of the three groups were significantly different(P＜0.05).The length of hospital staying and readmission rate of group B and C were lower than those of group A(P＜0.05).Conclusion Furosemide+nitroglycerin combined with neoactin or dopamine in the treatment of anterior wall STEMI patients with heart failure after primary PCI is more effective,can enhance patients'heart health,shorten the length of hospital stay,reduce the readmission rate,worthy of clinical promotion.
