Effect of exercise on cancer-related cognitive impairment in breast cancer patients:a Meta-analysis
10.3969/j.issn.1671-8283.2023.11.010
- VernacularTitle:运动对乳腺癌患者癌症相关认知障碍干预效果的Meta分析
- Author:
Yu BI
1
;
Ping ZHU
;
Yuanfeng LU
;
Aihua ZHANG
Author Information
1. 山东第一医科大学(山东省医学科学院)护理学院,山东泰安,271016
- Keywords:
exercise;
breast cancer;
cancer-related cognitive impairment;
Meta-Analysis
- From:
Modern Clinical Nursing
2023;22(11):68-75
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the intervention effect of exercise on cancer related cognitive impairment of breast cancer patients,and to provide evidence-based evidence for the choices of rehabilitation programs for cognitive impairment.Methods The PubMed,Embase,Web of Science,Cochrane Library,Joanna Briggs Institute Library(JBI),CINAHL,CNKI,Wanfang,VIP and CBM were searched by computer for randomized controlled trials on the impact of exercise on cancer-related cognitive impairment in patients with breast cancer.The retrieval time limit was from the establishment of the database to October 2022.The quality of the included studies was evaluated according to Cochrane Handbook 5.1.0.RevMan5.4 was used for meta-analysis.Results A total of 18 publications including 1310 patients were included.The results showed that exercise could improve self-reported cancer-related cognitive impairment[SMD=0.33,95%CI(0.21,0.46),P<0.001],executive function[SMD=-0.27,95%CI(-0.42,-0.11),P<0.001]and attention[SMD=-0.37,95%CI(-0.60,-0.14),P<0.01],alleviate cancer-related fatigue[SMD=-0.56,95%CI(-0.79,-0.34),P<0.001],and reduce depression[SMD=-0.73,95%CI(-1.17,-0.30),P<0.001],but it has no significant effect on the memory of patients with breast cancer[SMD=0.05,95%CI(-0.16,0.27),P=0.64].Conclusion Exercise can improve the self-reported cancer-related cognitive impairment,executive function and attention of breast cancer patients,alleviate cancer-related fatigue,reduce depression,but it has no significant effect on improving memory,which still needs further verification.
