An Autopsy Case of Agyria.
- Author:
Young Ill PARK
1
;
Joon Hee OH
;
Tae Sub SHIM
;
Je G CHI
Author Information
1. Department of Pediatrics, College of Medicine, Chung-Ang Univ, Korea.
- Publication Type:Original Article
- MeSH:
Autopsy*;
Birth Weight;
Brain;
Cerebellum;
Ear;
Estrogens, Conjugated (USP);
Head;
Humans;
Infant, Newborn;
Lissencephaly*;
Palate;
Pregnancy
- From:Journal of the Korean Pediatric Society
1979;22(9):799-802
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
An autopsy case of agyria in a newborn infant was reported. This neonate had her birth weight of 1.62kg after 40 weeks of gestation. The head circumference was 24cm(less than 3 percentile), and was slightly asymmetric. The brain weighed 60 grams. Fronto-occipital diameter was 7cm. And biparietal diameter was 6.5cm. Two small hemispheres were covered with opague congested leptomeninges, and barely no demonstrable gyrial pattern was recongnized. Interhemispheric fissure, Sylvian fissure and Hippocampal fissures was recognized together with poorly developed olfactory fissure. Cerebral mantle consisted of diffusely thick, 4 layered cortex that is hardly distinguishable rom underlying white matter. Multifocal granule cell heterotopias of cerebellum and neruonal heterotopia in interior Olivary nuclei were seen. Besides, dural anomalies and posterior fossa cyst were observed in this case. Extraneural anomalies consisted of ostium secundum atrial septal defet, low-set ears and high-arched palate.
