Experimental Studies of Effects of Ginseng and Steroids on Pneumococcal Endophthalmitis in Rabbits eyes.
- Author:
Yang Su RIM
1
Author Information
1. Department of Ophthalmology, National Medical Center, Seoul, Korea.
- Publication Type:Original Article
- MeSH:
Anterior Chamber;
Atropine;
Cornea;
Dexamethasone;
Edema;
Endophthalmitis*;
Panax*;
Rabbits*;
Steroids*;
Streptococcus pneumoniae
- From:Journal of the Korean Ophthalmological Society
1979;20(3):273-281
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The experimental endophthalmitis was obtained by the injection of pneumococcus into the anterior chamber of the rabbit's eyes and the effects of ginseng and steroids were observed. In one group, ginseng extract (50 mg/kg) was injected intraperitoneally for 6 days. In another group, dexamethasone (0.1 mg/kg) was injected intramuscularly and prednison(R) ophthalmic ointment used topically for 6 days. All groups were treated with atropine and colimycin-T@ ophthalmic ointment topically for 8 days. The eyes were examined clinically and histopathologically. The characteristic pictures of changes of peneumococcal endophthalmitis were stmrnal edema of the cornea by slit lamp biomicroscopic examination. The resuns were as follows: 1. In ginseng injection group, the stromal edema of cornea was more aggravated than control group. 2. In steroids injection group, the stromal edema of cornea was more aggravated than control group. 3. There was no notable difference between the changes in the ginseng injection group and steroids injection group.
