Risk factors of postoperative mortality of femoral neck fractures in elderly patients and construction of a nomogram predictive model
- VernacularTitle:老年股骨颈骨折患者术后死亡的危险因素及预测列线图的构建
- Author:
Zhipeng LI
1
;
Dawei HUAN
;
Zhaofeng YUAN
;
Yue QIU
;
Chao ZHANG
;
Tianwei XIA
;
Jirong SHEN
Author Information
1. 南京中医药大学附属医院(江苏省中医院),江苏省南京市 210004
- Keywords:
elderly;
femoral neck fracture;
mortality;
risk factor;
regression analysis;
nomogram prediction model
- From:
Chinese Journal of Tissue Engineering Research
2024;28(21):3361-3366
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:With a gradually aging population,improving the ability to screen for the risk of death after arthroplasty and implementing timely personalized intervention programs for the increasing number of elderly patients with femoral neck fractures is key to improving the postoperative status of patients and prolonging survival expectations. OBJECTIVE:To investigate the risk factors for postoperative mortality in elderly patients with femoral neck fractures and to construct a nomogram predictive model to predict their mortality risk. METHODS:The study was conducted on 155 elderly patients(≥65 years old)who underwent arthroplasty for femoral neck fracture from January 2016 to January 2021,and 147 patients who met the inclusion criteria were analyzed to collect clinical data that may affect the patients'postoperative mortality.Single-factor and multi-factor Cox regression analyses were successively used to screen independent risk factors associated with postoperative mortality.The column line graph model was constructed and validated using Rstudio software. RESULTS AND CONCLUSION:(1)Age,frailty(age-adjusted Charlson comorbidities score),preoperative activity status,osteoporosis,and postoperative serum albumin level were five independent risk factors for postoperative mortality in elderly patients with femoral neck fractures(P<0.05).(2)The nomogram predictive model was constructed based on the results of multifactorial analysis,with a consistency index of 0.819(95%CI:0.771-0.868).Receiver operating characteristic curve analysis showed that the area under curve for 1-year and 3-year survival prediction was 0.8543 and 0.7263,respectively,indicating that the nomogram predictive model has good discriminatory and predictive power;calibration curve and decision curve analysis also showed good model discriminative power and clinical utility value.(3)The constructed nomogram predictive model has good diagnostic efficacy and accuracy,and can effectively assess the risk of postoperative death of patients.
