Digital characteristics of brainstem morphology and age-related development in young children
- VernacularTitle:幼童脑干形态学与增龄发育的数字化特征
- Author:
Yanan LIU
1
;
Xing WANG
;
Kun LI
;
Ruifen SUN
;
Xueying MA
;
Lei ZHAO
;
Yuhang LIU
;
Yang YANG
;
Yunteng HAO
;
Ziyu LI
;
Shaojie ZHANG
;
Zhijun LI
Author Information
- Keywords: brainstem; radial line; area; intersection angle; MRI; morphological developmental feature; young children
- From: Chinese Journal of Tissue Engineering Research 2024;28(11):1730-1736
- CountryChina
- Language:Chinese
- Abstract: BACKGROUND:Previous brain studies have mostly focused on adults and fetuses,and the developmental characteristics of young children's brainstems have rarely been studied. OBJECTIVE:To observe the brainstem development characteristics of healthy young children and to explore the age-related differences and their correlation with sex. METHODS:From January 2019 to April 2022,a retrospective study of 3.0T MRI images of 174 children aged 2 to 6 years in the Affiliated Hospital of Inner Mongolia Medical University was conducted,and the median sagittal diameter,area and angle of the brainstem(including midbrain,pons and medulla oblongata)were measured. RESULTS AND CONCLUSION:There is an age-related increase in the anterior and posterior diameters of the midbrain,pons and medulla oblongata in the 2-5 years old group as well as in the longitudinal diameter and area of the midbrain,pons and medulla oblongata in the 2-6 years old group.Except for the longitudinal diameter of the medulla oblongata,all others show a positive correlation with age(r>0,P<0.05).In the 2-3 years old group and 4-5 years old group,the children are in the rapid growth and development stage,and these two age groups can be used as the key observation indicators for the development of young children.The anterior-posterior diameter,longitudinal diameter,area of the pons and total brainstem area are strongly correlated with age,which can be used as the key observation indicators for the brainstem development in young children.
