Comparative Study on Different Serology Risk Stratification Combined With Endoscopy for Screening of Early Gastric Cancer
10.3969/j.issn.1008-7125.2023.11.005
- VernacularTitle:不同血清学危险分层联合内镜检查筛查早期胃癌的比较研究
- Author:
Yueping ZHENG
1
;
Ping JIANG
;
Zhi NI
;
Rongchun ZHANG
Author Information
1. 厦门弘爱医院消化内科(361016)
- Keywords:
Helicobacter pylori;
Stomach Neoplasms;
Screening;
The Novel Scoring System;
ABC Method
- From:Chinese Journal of Gastroenterology
2023;28(11):672-676
- CountryChina
- Language:Chinese
-
Abstract:
Background:One effective method for detecting stomach cancer is serological screening.Aims:To improve the prognosis and better direct clinical practice,this research compares the usefulness of the new scoring system and the ABC method in the screening of high-risk lesions of gastric cancer.Methods:This study involved the consecutive enrollment of 2 306 individuals(of whom 1 232 were male and 1 074 were female)who had gastroscopy at the Physical Examination Department of Xiamen Humanity Hospital between December 2020 and December 2022 and were above the age of 40.Before endoscopy,the population was classified as low-risk,intermediate-risk,and high-risk based on the serological ABC method and the new scoring system,respectively,and based on the age,gender,serum Helicobacter pylori antibody,PGR,and G-17 test findings of the studied population.An analysis was conducted on the identification of high-risk lesions of stomach cancer using the two distinct approaches,and the usefulness of the two distinct techniques for identifying high-risk lesions associated with stomach cancer was assessed.Results:Based on the serological ABC method of 2 306 patients,there were 1 293 cases in the low-risk group,856 cases in the intermediate-risk group,and 157 cases in the high-risk group.Of the three groups,759 cases(58.7%)had high-risk lesions of gastric cancer,492 cases(57.5%)in the intermediate-risk group,and 82 cases(52.2%)in the high-risk group.There were 1 899 cases in the low-risk category,383 cases in the intermediate-risk group,and 27 cases in the high-risk group,based on the novel scoring system.Among them,1 044 patients had high-risk stomach cancer lesions found.There were 18 instances(75.0%)in the high-risk group and 271 cases(70.8%)in the intermediate-risk group.The identification rate of high-risk lesions of gastric cancer in the new scoring method increases progressively as the group grade rises(χ2=35.482,P<0.001).Conclusions:While both approaches are useful for identifying high-risk gastric cancer lesions,the novel scoring system may be more beneficial for identifying these lesions early on.
