Progress of Research on Clinical Application of Histological Remission Assessment in Ulcerative Colitis
10.3969/j.issn.1008-7125.2023.02.008
- VernacularTitle:溃疡性结肠炎组织学缓解评估在临床应用中的研究进展
- Author:
Linmei XIAO
1
;
Hongjie ZHANG
Author Information
1. 南京医科大学第一附属医院消化内科(210029)
- Keywords:
Colitis,Ulcerative;
Histological Remission;
Pathological Score
- From:
Chinese Journal of Gastroenterology
2023;28(2):115-119
- CountryChina
- Language:Chinese
-
Abstract:
Ulcerative colitis(UC)is a chronic non-specific inflammatory disease of the intestine.With the application of biological agents,more and more UC patients have achieved endoscopic healing,but about one-third of UC patients achieving endoscopic healing still have histological activity,and this sustained histological activity may be associated with disease recurrence.Therefore,histological remission of UC has received increasing attention in clinical practice.In 2020,European Crohn's and Colitis Organization(ECCO)proposed histological remission as an important therapeutic target for UC.In 2021,the International Organization for the Study of Inflammatory Bowel Disease(IOIBD)in its latest program on standard treatment pointed out that histological remission will be used as a measure of deep remission.This article reviewed the progress of research on clinical application of histological remission assessment in UC.