Research progress of mesenchymal stem cells in endometriosis
10.11958/20231271
- VernacularTitle:间充质干细胞在子宫内膜异位症中的研究进展
- Author:
Xinyao WANG
1
;
Hui YANG
;
Bingbing LI
Author Information
1. 济宁医学院临床医学院(邮编 272000)
- Keywords:
endometriosis;
mesenchymal stem cells;
cell movement;
inflammation;
pathogenesis
- From:
Tianjin Medical Journal
2024;52(2):215-219
- CountryChina
- Language:Chinese
-
Abstract:
Endometriosis is a common chronic gynecological disease,and its pathogenesis has not been fully elucidated.Mesenchymal stem cells are a kind of pluripotent stem cells with multi-directional differentiation potential derived from mesoderm,which can differentiate into a variety of tissues and organs.Endometrial mesenchymal stem cells,menstrual blood-derived mesenchymal stem cells,adipose mesenchymal stem cells,bone marrow mesenchymal stem cells and umbilical cord blood mesenchymal stem cells can participate in the pathogenesis of endometriosis from cell proliferation and differentiation,ectopic migration,angiogenesis,inflammatory response and fibrosis formation,and play a certain role in progression of the disease.Mesenchymal stem cells provide new ideas for elucidating the pathogenesis of endometriosis,and may also become a potential method for the treatment of endometriosis.
