Research progress on the roles of non-coding RNA in chemotherapy resistance of breast cancer
10.11904/j.issn.1002-3070.2023.05.012
- VernacularTitle:非编码RNA在乳腺癌化疗耐药中作用的研究进展
- Author:
Xinping WANG
1
;
Ziyun ZHANG
;
Xuedong WANG
Author Information
1. 安徽理工大学医学院(淮南 232001)
- Keywords:
Breast cancer;
Non-coding RNA;
Chemotherapy resistance
- From:
Practical Oncology Journal
2023;37(5):454-458
- CountryChina
- Language:Chinese
-
Abstract:
Breast cancer is a kind of malignant tumor with high heterogeneity.Chemotherapy is one of the important treat-ments for advanced breast cancer or postoperative breast cancer.However,the emergence of secondary drug resistance weakens the ef-fectiveness of chemotherapy,leading to a poor prognosis for patients.In recent years,more and more studies have shown that non-coding RNA(ncRNA)can promote breast cancer chemotherapy resistance by regulating cell proliferation,tumor stem cell characteris-tics,epithelial-mesenchymal transition and other processes.This article reviews the research on the mechanism of ncRNA-mediated chemotherapy resistance in breast cancer.
