The research progress of the actions of mast cells in sepsis
10.3969/j.issn.1006-5725.2024.05.002
- VernacularTitle:肥大细胞在脓毒症中的作用研究进展
- Author:
Junling WANG
1
,
2
;
Mengmeng ZHAN
;
Zhaolong ZHANG
;
Shaoheng HE
;
Bingyu QIN
Author Information
1. 郑州大学人民医院河南省人民医院重症医学部(郑州 450003)
2. 锦州医科大学附属第一医院变态反应与临床免疫研究中心(辽宁锦州 121001)
- Keywords:
sepsis;
mast cell;
potential roles
- From:
The Journal of Practical Medicine
2024;40(5):596-600
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis is a life-threatening organ dysfunction,which is caused by the body's uncontrolled immune response to infection.Tissue masts cells(MC),derived from blood mast cell progenitors,are one of the classical effector cells in inflammatory response.MC plays an important role in sepsis via secreting a variety of inflammatory mediators and cytokines.Here,we summarized the potential roles of MC in sepsis,which is expected to provide novel ideas for the future research on the novel mechanisms of MC in sepsis.
