Research progress on the interaction between macro-phages and fibroblasts in ARDS pulmonary fibrosis

VernacularTitle:急性呼吸窘迫综合征肺纤维化中巨噬细胞和成纤维细胞相互作用的研究进展
Author: Aiqin LI ^{1
,

2} ; Zhen ZHANG ; Ya'nan XU ; Jinyuan ZHU ; Xu ZHANG
Author Information

1. 宁夏医科大学总医院,医学研究院银川 750004
2. 宁夏医科大学总医院,日间病房银川 750004
Keywords: acute respiratory distress syndrome; pulmonary fibrosis; macrophage; fibroblasts
From: The Journal of Practical Medicine 2024;40(4):571-574
CountryChina
Language:Chinese
Abstract: Acute respimtory distress syndrome(ARDS)is an acute diffuse inflammatory lung injury caused by various internal and external lung injury factors.It has complex pathogenesis,rapid onset and high mortality,which seriously endangers human life and health.Pulmonary fibrosis is one of the important pathologic processes of ARDS occurrence and development,and it is also an important cause of death in ARDS patients.To a certain extent,the severity of pulmonary fibrosis in ARDS is determined by the dynamic balance of macrophage-fibroblast interactions.Therefore,this article aims to review the interaction mechanism of macrophage-fibroblasts in the pro-cess of ARDS pulmonary fibrosis,and provide new methods and ideas for the diagnosis and treatment of ARDS pul-monary fibrosis.