Correlation analysis of glucose and lipid metabolism indicators combined with antiphospholipid antibodies on prognosis of patients with atherosclerosis
10.3969/j.issn.1006-5725.2024.03.008
- VernacularTitle:糖脂代谢指标联合抗磷脂抗体对动脉粥样硬化患者预后的预测价值
- Author:
Jia CUI
1
;
Mingming ZHANG
;
Na WANG
;
Wei GAO
;
Fei LI
Author Information
1. 河北省人民医院 检验科(石家庄 050051)
- Keywords:
atherosclerosis;
indicators of glucose and lipid metabolism;
antiphospholipid antibody;
prognosis
- From:
The Journal of Practical Medicine
2024;40(3):326-329
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation of glucose and lipid metabolism indicators combined with antiphospholipid antibodies with the prognosis of patients with atherosclerosis.Methods A total of 128 patients with atherosclerosis treated in our hospital from April 2021 to March 2023 were selected as study group,and 48 healthy individuals as control group.Glycolipid metabolism indexes and antiphospholipid antibody level of the two groups were compared,and the predictive value of glycolipid metabolism indexes,antiphospholipid antibodies and combined detection for the prognosis of patients with atherosclerosis were analyzed by ROC.Results TC,TG,ACL,and anti-β2-GP1 in the study group was higher than that in the control group(P＜0.05).The study group was divided into two sub-groups according to the prognosis.The expression level of TC,TG,ACL,and anti-β 2-GP1 in poor prognosis group was higher than that in good prognosis group(P＜0.05).TC,TG,ACL,and anti-β 2-GP1 was positively correlated with the poor prognosis of patients with atherosclerosis(P＜0.05).ROC curve showed that the predictive value of six combined tests for the prognosis of patients with atherosclerosis was higher than that of single test of TC,TG,ACL,and anti-β2-GP1(P＜0.05).Conclusion The combined detection of TC,TG,ACL,and anti-β2-GP1 has high predictive value for the prognosis of patients with atherosclerosis.
