Research progress of the relationship between high fat diet-Induced gastrointestinal microbiota and gastro-intestinal cancer
10.3969/j.issn.1006-5725.2024.01.022
- VernacularTitle:高脂饮食引发胃肠菌群改变与胃肠肿瘤关系的研究进展
- Author:
Qi WU
1
,
2
;
Le BU
;
Bei XU
Author Information
1. 安徽理工大学医学院 (安徽淮南 232001)
2. 上海市第十人民医院内分泌科 (上海 200072)
- Keywords:
high fat diet;
gastrointestinal microbiota;
gastrointestinal cancer
- From:
The Journal of Practical Medicine
2024;40(1):123-128
- CountryChina
- Language:Chinese
-
Abstract:
In healthy individuals,there is a favourable balance between commensal and potentially patho-genic bacteria.When the balance is broken,the host might suffer from gastrointestinal cancer.Studies have shown that high-fat diet can alter the composition of gastrointestinal microbiota,gastrointestinal microbiota may promote gastrointestinal cancer by affecting metabolites of gastrointestinal microbiota,leading to loss of gastrointestinal barrier function,suppressing anti-tumor immunity,etc.In this work,we will summary the current knowledge on relations and possible mechanisms of high-fat diet-associated gastrointestinal microbiota and gastrointestinal cancer.To provide new ideas for the treatment of gastrointestinal cancer.
